eGFR (estimert glomerulær filtrasjonshastighet) er et mål som anslår hvor godt nyrene filtrerer avfallsstoffer fra blodet. Den beregnes ved hjelp av serumkreatininnivåer sammen med faktorer som alder, kroppsstørrelse og kjønn. eGFR er en viktig indikator på nyrefunksjon, og bidrar til å avgjøre hvor effektivt nyrene fungerer. En lavere eGFR antyder redusert nyrefunksjon, noe som kan indikere nyresykdom eller skade.
Testing eGFR levels is beneficial for individuals at risk of kidney disease, such as those with diabetes, high blood pressure, heart disease, or a family history of kidney failure. It’s also important for older adults, as kidney function can decline with age. People who are taking medications that can affect kidney function should also monitor their eGFR regularly.
Improving eGFR levels involves managing any underlying conditions that are affecting kidney function. This can include controlling blood sugar levels in diabetes, managing blood pressure, reducing salt intake, and maintaining a healthy weight. Avoiding medications that can harm the kidneys and reducing the use of NSAIDs (non-steroidal anti-inflammatory drugs) can also help. Regular monitoring and maintaining a balanced diet with controlled protein intake are important in managing kidney health.
Several factors can affect eGFR levels. Chronic conditions like diabetes and high blood pressure can lead to a decrease in eGFR over time. Age is also a factor, as kidney function naturally declines with age. Certain medications, particularly those that can be toxic to the kidneys, can impact eGFR. Ethnicity and muscle mass can influence creatinine levels, and thus the eGFR calculation. Dehydration and acute illnesses can also temporarily affect kidney function and eGFR.
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