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Transglutaminase IgG

Transglutaminase IgG (tTG-IgG) er en blodtest som påviser IgG-antistoffer mot vevstransglutaminase, et enzym i tarmens slimhinne. Den brukes hovedsakelig for å hjelpe til med å diagnostisere cøliaki, spesielt hos personer med IgA-mangel eller uklare tTG-IgA-resultater, ved å indikere en immunreaksjon på gluten.

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What are the typical symptoms indicating a need for the Transglutaminase IgG test?

Symptoms that might indicate a need for testing include gastrointestinal issues like chronic diarrhea and abdominal pain, as well as extraintestinal symptoms such as anemia, dermatitis herpetiformis (a skin rash), and growth problems in children, all of which could suggest celiac disease.

How is the Transglutaminase IgG test performed?

The test requires a blood sample from the patient. This sample is analyzed in a laboratory to measure the levels of IgG antibodies against tissue transglutaminase. Elevated levels of these antibodies suggest an immune reaction to gluten.

What causes positive results in a Transglutaminase IgG test?

A positive result typically indicates an autoimmune response to gluten, as seen in celiac disease, where the body’s immune system mistakenly targets the small intestine. This reaction is triggered by the ingestion of gluten-containing foods.

Who should undergo the Transglutaminase IgG test?

The tTG-IgG test is recommended for individuals who show symptoms of celiac disease but have an IgA deficiency, making the tTG-IgA test less useful. Symptoms prompting this test include chronic diarrhea, abdominal pain, bloating, weight loss, and malnutrition.

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Glutenintoleranse Test – Cøliaki
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Blodprøver

Ved symptomer som fordøyelsesbesvær, tretthet eller andre problemer som kan være knyttet til glutenintoleranse, kan det være lurt å ta en glutenintoleransetest. Denne testen identifiserer tilstedeværelsen av IgA-antistoffer mot vevstransglutaminase (tTG), som er en viktig markør for cøliaki. Cøliaki er en alvorlig autoimmun sykdom som utløses av gluten, og det er viktig å finne ut om man har det.

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What are the typical symptoms indicating a need for the Transglutaminase IgG test?
How is the Transglutaminase IgG test performed?
What causes positive results in a Transglutaminase IgG test?
Who should undergo the Transglutaminase IgG test?
What are the typical symptoms indicating a need for the Transglutaminase IgG test?
How is the Transglutaminase IgG test performed?
What causes positive results in a Transglutaminase IgG test?
Who should undergo the Transglutaminase IgG test?
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